Deferiprone Rescues Behavioral Deficits Induced by Mild Iron Exposure in a Mouse Model of Alpha-Synuclein Aggregation

Parkinson’s disease (PD) is the most common neurodegenerative movement disorder, and its causes remain unknown. A major hallmark of the disease is the increasing presence of aggregated alpha-synuclein (aSyn). Furthermore, there is a solid consensus on iron (Fe) accumulation in several regions of PD...

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Pubblicato in:Neuromolecular Med
Autori principali: Carboni, Eleonora, Tatenhorst, Lars, Tönges, Lars, Barski, Elisabeth, Dambeck, Vivian, Bähr, Mathias, Lingor, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2017
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Original Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570801/
https://ncbi.nlm.nih.gov/pubmed/28623611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12017-017-8447-9
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