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BRG1 promotes endothelial Mrtf transcription to estab-lish embryonic capillary integrity

OBJECTIVE: The chromatin remodeling enzyme BRG1 transcriptionally regulates target genes important for early blood vessel development and primitive hematopoiesis. However, because Brg1 deletion in vascular progenitor cells results in lethal anemia by embryonic day 10.5 (E10.5), roles for BRG1 in emb...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Menendez, Matthew T., Ong, E-Ching, Shepherd, Brian T., Muthukumar, Vijay, Silasi-Mansat, Robert, Lupu, Florea, Griffin, Courtney T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570645/
https://ncbi.nlm.nih.gov/pubmed/28729363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309785
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