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A systems approach reveals distinct metabolic strategies among the NCI-60 cancer cell lines

The metabolic phenotype of cancer cells is reflected by the metabolites they consume and by the byproducts they release. Here, we use quantitative, extracellular metabolomic data of the NCI-60 panel and a novel computational method to generate 120 condition-specific cancer cell line metabolic models...

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Bibliografiske detaljer
Udgivet i:PLoS Comput Biol
Main Authors: Aurich, Maike K., Fleming, Ronan M. T., Thiele, Ines
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570491/
https://ncbi.nlm.nih.gov/pubmed/28806730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005698
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