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Epithelial calcineurin controls microbiota-dependent intestinal tumor development
Inflammation-associated pathways are active in intestinal epithelial cells (IECs) and contribute to the pathogenesis of colorectal cancer (CRC). Calcineurin, a phosphatase required for the activation of the nuclear factor of activated T cells (NFAT) family of transcription factors, shows increased e...
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| Publicat a: | Nat Med |
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| Autors principals: | , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5570457/ https://ncbi.nlm.nih.gov/pubmed/27043494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4072 |
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