Is more better? The impact of extended adjuvant temozolomide in newly diagnosed glioblastoma: a secondary analysis of EORTC and NRG Oncology/RTOG

BACKGROUND: Radiation with concurrent and adjuvant (6 cycles) temozolomide (TMZ) is the established standard of postsurgical care for newly diagnosed glioblastoma (GBM). This regimen has been adopted with variations, including extending TMZ beyond 6 cycles. The optimal duration of maintenance therap...

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Vydáno v:Neuro Oncol
Hlavní autoři: Blumenthal, Deborah T., Gorlia, Thierry, Gilbert, Mark R., Kim, Michelle M., Burt Nabors, L., Mason, Warren P., Hegi, Monika E., Zhang, Peixin, Golfinopoulos, Vassilis, Perry, James R., Hyun Nam, Do, Erridge, Sara C., Corn, Benjamin W., Mirimanoff, René O, Brown, Paul D., Baumert, Brigitta G., Mehta, Minesh P., van den Bent, Martin J., Reardon, David A., Weller, Michael, Stupp, Roger
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
Clinical Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570239/
https://ncbi.nlm.nih.gov/pubmed/28371907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox025
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