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Is more better? The impact of extended adjuvant temozolomide in newly diagnosed glioblastoma: a secondary analysis of EORTC and NRG Oncology/RTOG

BACKGROUND: Radiation with concurrent and adjuvant (6 cycles) temozolomide (TMZ) is the established standard of postsurgical care for newly diagnosed glioblastoma (GBM). This regimen has been adopted with variations, including extending TMZ beyond 6 cycles. The optimal duration of maintenance therap...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Blumenthal, Deborah T., Gorlia, Thierry, Gilbert, Mark R., Kim, Michelle M., Burt Nabors, L., Mason, Warren P., Hegi, Monika E., Zhang, Peixin, Golfinopoulos, Vassilis, Perry, James R., Hyun Nam, Do, Erridge, Sara C., Corn, Benjamin W., Mirimanoff, René O, Brown, Paul D., Baumert, Brigitta G., Mehta, Minesh P., van den Bent, Martin J., Reardon, David A., Weller, Michael, Stupp, Roger
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570239/
https://ncbi.nlm.nih.gov/pubmed/28371907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox025
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