Is more better? The impact of extended adjuvant temozolomide in newly diagnosed glioblastoma: a secondary analysis of EORTC and NRG Oncology/RTOG

BACKGROUND: Radiation with concurrent and adjuvant (6 cycles) temozolomide (TMZ) is the established standard of postsurgical care for newly diagnosed glioblastoma (GBM). This regimen has been adopted with variations, including extending TMZ beyond 6 cycles. The optimal duration of maintenance therap...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Blumenthal, Deborah T., Gorlia, Thierry, Gilbert, Mark R., Kim, Michelle M., Burt Nabors, L., Mason, Warren P., Hegi, Monika E., Zhang, Peixin, Golfinopoulos, Vassilis, Perry, James R., Hyun Nam, Do, Erridge, Sara C., Corn, Benjamin W., Mirimanoff, René O, Brown, Paul D., Baumert, Brigitta G., Mehta, Minesh P., van den Bent, Martin J., Reardon, David A., Weller, Michael, Stupp, Roger
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
Schlagworte:
Clinical Investigations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570239/
https://ncbi.nlm.nih.gov/pubmed/28371907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox025
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