Piwi interacts with chromatin at nuclear pores and promiscuously binds nuclear transcripts in Drosophila ovarian somatic cells

Piwi in a complex with Piwi-interacting RNAs (piRNAs) triggers transcriptional silencing of transposable elements (TEs) in Drosophila ovaries, thus ensuring genome stability. To do this, Piwi must scan the nascent transcripts of genes and TEs for complementarity to piRNAs. The mechanism of this scan...

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Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: Ilyin, Artem A., Ryazansky, Sergei S., Doronin, Semen A., Olenkina, Oxana M., Mikhaleva, Elena A., Yakushev, Evgeny Y., Abramov, Yuri A., Belyakin, Stepan N., Ivankin, Anton V., Pindyurin, Alexey V., Gvozdev, Vladimir A., Klenov, Mikhail S., Shevelyov, Yuri Y.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2017
Konular:
Gene regulation, Chromatin and Epigenetics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570135/
https://ncbi.nlm.nih.gov/pubmed/28472469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx355
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