Cell-type-specific genome editing with a microRNA-responsive CRISPR–Cas9 switch

The CRISPR–Cas9 system is a powerful genome-editing tool useful in a variety of biotechnology and biomedical applications. Here we developed a synthetic RNA-based, microRNA (miRNA)-responsive CRISPR–Cas9 system (miR-Cas9 switch) in which the genome editing activity of Cas9 can be modulated through e...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Hirosawa, Moe, Fujita, Yoshihiko, Parr, Callum J. C., Hayashi, Karin, Kashida, Shunnichi, Hotta, Akitsu, Woltjen, Knut, Saito, Hirohide
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
Methods Online
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570128/
https://ncbi.nlm.nih.gov/pubmed/28525578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx309
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky