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Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells
Nuclear factor TDP-43 is known to play an important role in several neurodegenerative pathologies. In general, TDP-43 is an abundant protein within the eukaryotic nucleus that binds to many coding and non-coding RNAs and influence their processing. Using Drosophila, we have performed a functional sc...
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| 發表在: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5570092/ https://ncbi.nlm.nih.gov/pubmed/28575377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx477 |
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