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Adaptive HIV-1 evolutionary trajectories are constrained by protein stability
Despite the use of combination antiretroviral drugs for the treatment of HIV-1 infection, the emergence of drug resistance remains a problem. Resistance may be conferred either by a single mutation or a concerted set of mutations. The involvement of multiple mutations can arise due to interactions b...
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| Publicado no: | Virus Evol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5570062/ https://ncbi.nlm.nih.gov/pubmed/28852572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ve/vex019 |
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