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The origins of the evolutionary signal used to predict protein-protein interactions

BACKGROUND: The correlation of genetic distances between pairs of protein sequence alignments has been used to infer protein-protein interactions. It has been suggested that these correlations are based on the signal of co-evolution between interacting proteins. However, although mutations in differ...

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Detalhes bibliográficos
Main Authors: Swapna, Lakshmipuram S, Srinivasan, Narayanaswamy, Robertson, David L, Lovell, Simon C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537733/
https://ncbi.nlm.nih.gov/pubmed/23217198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-12-238
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