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Comparison of tertiary structures of proteins in protein-protein complexes with unbound forms suggests prevalence of allostery in signalling proteins

BACKGROUND: Most signalling and regulatory proteins participate in transient protein-protein interactions during biological processes. They usually serve as key regulators of various cellular processes and are often stable in both protein-bound and unbound forms. Availability of high-resolution stru...

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Detalhes bibliográficos
Main Authors: Swapna, Lakshmipuram S, Mahajan, Swapnil, de Brevern, Alexandre G, Srinivasan, Narayanaswamy
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427047/
https://ncbi.nlm.nih.gov/pubmed/22554255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-12-6
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