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Identification of Local Conformational Similarity in Structurally Variable Regions of Homologous Proteins Using Protein Blocks

Structure comparison tools can be used to align related protein structures to identify structurally conserved and variable regions and to infer functional and evolutionary relationships. While the conserved regions often superimpose well, the variable regions appear non superimposable. Differences i...

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Detalhes bibliográficos
Main Authors: Agarwal, Garima, Mahajan, Swapnil, Srinivasan, Narayanaswamy, de Brevern, Alexandre G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060819/
https://ncbi.nlm.nih.gov/pubmed/21445259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017826
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