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Extent of Structural Asymmetry in Homodimeric Proteins: Prevalence and Relevance

Most homodimeric proteins have symmetric structure. Although symmetry is known to confer structural and functional advantage, asymmetric organization is also observed. Using a non-redundant dataset of 223 high-resolution crystal structures of biologically relevant homodimers, we address questions on...

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Hlavní autoři: Swapna, Lakshmipuram Seshadri, Srikeerthana, Kuchi, Srinivasan, Narayanaswamy
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358323/
https://ncbi.nlm.nih.gov/pubmed/22629324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036688
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