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Constraints on HIV-1 Diversity from Protein Structure

The high rate of HIV-1 evolution contributes to immune escape, enables the virus to escape drug therapy, and may underlie the difficulty of producing an effective vaccine. Identifying constraints on HIV evolution is therefore of prime importance. To investigate this problem, we examined the relation...

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Detalles Bibliográficos
Autores principales: Woo, Jeongmin, Robertson, David L., Lovell, Simon C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004343/
https://ncbi.nlm.nih.gov/pubmed/20881050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00702-10
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