Evidence for double-strand break mediated mitochondrial DNA replication in Saccharomyces cerevisiae

The mechanism of mitochondrial DNA (mtDNA) replication in Saccharomyces cerevisiae is controversial. Evidence exists for double-strand break (DSB) mediated recombination-dependent replication at mitochondrial replication origin ori5 in hypersuppressive ρ(−) cells. However, it is not clear if this re...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Prasai, Kanchanjunga, Robinson, Lucy C., Scott, Rona S., Tatchell, Kelly, Harrison, Lynn
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
Genome Integrity, Repair and Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569933/
https://ncbi.nlm.nih.gov/pubmed/28549155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx443
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