Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor.

The extracellular protease urokinase is known to be crucially involved in morphogenesis, tissue repair and tumor invasion by mediating matrix degradation and cell migration. Hepatocyte growth factor/scatter factor (HGF/SF) is a secretory product of stromal fibroblasts, sharing structural motifs with...

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Hlavní autoři: Naldini, L, Tamagnone, L, Vigna, E, Sachs, M, Hartmann, G, Birchmeier, W, Daikuhara, Y, Tsubouchi, H, Blasi, F, Comoglio, P M
Médium: Artigo
Jazyk:Inglês
Vydáno: 1992
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC556958/
https://ncbi.nlm.nih.gov/pubmed/1334458
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