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Evaluation of three read-depth based CNV detection tools using whole-exome sequencing data

BACKGROUND: Whole exome sequencing (WES) has been widely accepted as a robust and cost-effective approach for clinical genetic testing of small sequence variants. Detection of copy number variants (CNV) within WES data have become possible through the development of various algorithms and software p...

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Detalhes bibliográficos
Publicado no:Mol Cytogenet
Main Authors: Yao, Ruen, Zhang, Cheng, Yu, Tingting, Li, Niu, Hu, Xuyun, Wang, Xiumin, Wang, Jian, Shen, Yiping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569469/
https://ncbi.nlm.nih.gov/pubmed/28852425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13039-017-0333-5
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