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Modeling Read Counts for CNV Detection in Exome Sequencing Data
Varying depth of high-throughput sequencing reads along a chromosome makes it possible to observe copy number variants (CNVs) in a sample relative to a reference. In exome and other targeted sequencing projects, technical factors increase variation in read depth while reducing the number of observed...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
De Gruyter
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3517018/ https://ncbi.nlm.nih.gov/pubmed/23089826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2202/1544-6115.1732 |
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