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Amoeboid-mesenchymal migration plasticity promotes invasion only in complex heterogeneous microenvironments

During tissue invasion individual tumor cells exhibit two interconvertible migration modes, namely mesenchymal and amoeboid migration. The cellular microenvironment triggers the switch between both modes, thereby allowing adaptation to dynamic conditions. It is, however, unclear if this amoeboid-mes...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Talkenberger, Katrin, Cavalcanti-Adam, Elisabetta Ada, Voss-Böhme, Anja, Deutsch, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569097/
https://ncbi.nlm.nih.gov/pubmed/28835679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09300-3
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