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Oncogenic v-Abl tyrosine kinase can inhibit or stimulate growth, depending on the cell context.

The v-abl oncogene of Abelson murine leukemia virus (A-MuLV) induces two opposite phenotypes in NIH3T3 cells. In the majority of cells, v-abl causes a growth arrest at the G1 phase of the cell cycle; while in a minority of cells, v-abl abrogates the requirement for growth factors. Using temperature...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Renshaw, M W, Kipreos, E T, Albrecht, M R, Wang, J Y
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1992
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC556905/
https://ncbi.nlm.nih.gov/pubmed/1396587
Tagiau: Ychwanegu Tag
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