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Development of a novel immunoassay to detect interactions with the transactivation domain of p53: application to screening of new drugs
Tumor protein p53 acts as a trans-activator that negatively regulates cell division by controlling a set of genes required for cell cycle regulation, making it a tumor suppressor in different types of tumors. Because the transcriptional activity of p53 plays an important role in the occurrence and d...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5569017/ https://ncbi.nlm.nih.gov/pubmed/28835687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09574-7 |
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