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Determination of the enantiomeric purity of epinephrine by HPLC with circular dichroism detection

Several hundred drug substances approved by the U.S. Food and Drug Administration are chiral molecules. For the enantiomeric purity assessment, current practice is to develop separation techniques using chiral columns or mobile phase modifiers to separate enantiomers before detection. An alternative...

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Bibliographic Details
Published in:J Liq Chromatogr Relat Technol
Main Authors: Kirkpatrick, Douglas, Yang, Jingyue, Trehy, Michael
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568804/
https://ncbi.nlm.nih.gov/pubmed/28845100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10826076.2017.1333962
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