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Determination of the enantiomeric purity of epinephrine by HPLC with circular dichroism detection

Several hundred drug substances approved by the U.S. Food and Drug Administration are chiral molecules. For the enantiomeric purity assessment, current practice is to develop separation techniques using chiral columns or mobile phase modifiers to separate enantiomers before detection. An alternative...

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Detalhes bibliográficos
Publicado no:J Liq Chromatogr Relat Technol
Main Authors: Kirkpatrick, Douglas, Yang, Jingyue, Trehy, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568804/
https://ncbi.nlm.nih.gov/pubmed/28845100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10826076.2017.1333962
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