Type I IFN Is Necessary and Sufficient for Inflammation-Induced Red Blood Cell Alloimmunization in Mice

During RBC transfusion, production of alloantibodies against RBC non-ABO Ags can cause hemolytic transfusion reactions and limit availability of compatible blood products, resulting in anemia-associated morbidity and mortality. Multiple studies have established that certain inflammatory disorders an...

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Publicado en:J Immunol
Main Authors: Gibb, David R., Liu, Jingchun, Natarajan, Prabitha, Santhanakrishnan, Manjula, Madrid, David J., Eisenbarth, Stephanie C., Zimring, James C., Iwasaki, Akiko, Hendrickson, Jeanne E.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568771/
https://ncbi.nlm.nih.gov/pubmed/28630094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700401
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