CD4 Depletion or CD40L Blockade Results in Antigen-Specific Tolerance in a Red Blood Cell Alloimmunization Model

Approximately 3–10% of human red blood cell (RBC) transfusion recipients form alloantibodies to non-self, non-ABO blood group antigens expressed on donor RBCs, with these alloantibodies having the potential to be clinically significant in transfusion and pregnancy settings. However, the majority of...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Natarajan, Prabitha, Liu, Dong, Patel, Seema R., Santhanakrishnan, Manjula, Beitler, Daniel, Liu, Jingchun, Gibb, David R., Liepkalns, Justine S., Madrid, David J., Eisenbarth, Stephanie C., Stowell, Sean R., Hendrickson, Jeanne E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545689/
https://ncbi.nlm.nih.gov/pubmed/28824633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00907
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