B cells require type 1 interferon to produce alloantibodies to transfused KEL-expressing RBCs in mice

BACKGROUND: Alloantibodies to RBC antigens can cause significant hemolytic events. Prior studies have demonstrated that inflammatory stimuli in animal models and inflammatory states in humans, including autoimmunity and viremia, promote alloimmunization. However, molecular mechanisms underlying thes...

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Detalhes bibliográficos
Publicado no:Transfusion
Main Authors: Gibb, David R., Liu, Jingchun, Santhanakrishnan, Manjula, Natarajan, Prabitha, Madrid, David J., Patel, Seema, Eisenbarth, Stephanie C., Tormey, Christopher A., Stowell, Sean R., Iwasaki, Akiko, Hendrickson, Jeanne E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745367/
https://ncbi.nlm.nih.gov/pubmed/28836263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/trf.14288
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