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B cells require type 1 interferon to produce alloantibodies to transfused KEL-expressing RBCs in mice

BACKGROUND: Alloantibodies to RBC antigens can cause significant hemolytic events. Prior studies have demonstrated that inflammatory stimuli in animal models and inflammatory states in humans, including autoimmunity and viremia, promote alloimmunization. However, molecular mechanisms underlying thes...

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Dades bibliogràfiques
Publicat a:Transfusion
Autors principals: Gibb, David R., Liu, Jingchun, Santhanakrishnan, Manjula, Natarajan, Prabitha, Madrid, David J., Patel, Seema, Eisenbarth, Stephanie C., Tormey, Christopher A., Stowell, Sean R., Iwasaki, Akiko, Hendrickson, Jeanne E.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745367/
https://ncbi.nlm.nih.gov/pubmed/28836263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/trf.14288
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