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Decoding of position in the developing neural tube from antiparallel morphogen gradients

Like many developing tissues, the vertebrate neural tube is patterned by antiparallel morphogen gradients. To understand how these inputs are interpreted, we measured morphogen signaling and target gene expression in mouse embryos and chick ex vivo assays. From these data, we derived and validated a...

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Détails bibliographiques
Publié dans:Science
Auteurs principaux: Zagorski, Marcin, Tabata, Yoji, Brandenberg, Nathalie, Lutolf, Matthias, Tkačik, Gašper, Bollenbach, Tobias, Briscoe, James, Kicheva, Anna
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568706/
https://ncbi.nlm.nih.gov/pubmed/28663499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aam5887
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