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Decoding of position in the developing neural tube from antiparallel morphogen gradients

Like many developing tissues, the vertebrate neural tube is patterned by antiparallel morphogen gradients. To understand how these inputs are interpreted, we measured morphogen signaling and target gene expression in mouse embryos and chick ex vivo assays. From these data, we derived and validated a...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Zagorski, Marcin, Tabata, Yoji, Brandenberg, Nathalie, Lutolf, Matthias, Tkačik, Gašper, Bollenbach, Tobias, Briscoe, James, Kicheva, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568706/
https://ncbi.nlm.nih.gov/pubmed/28663499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aam5887
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