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Mixed pH-Sensitive Polymeric Micelles for Combination Drug Delivery

PURPOSE: To prepare mixed polymeric micelles that can carry two different drugs, doxorubicin (DOX) and 17-hydroxyethylamino-17-demethoxygeldanamycin (GDM-OH), for combination cancer chemotherapy. METHODS: The pH-sensitive micelles were prepared from poly (ethylene glycol)-poly(aspartate hydrazide) b...

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Bibliographic Details
Published in:Pharm Res
Main Authors: Bae, Younsoo, Alani, Adam W. G., Rockich, Nicole C., Chung Lai, T. S. Z., Kwon, Glen S.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568702/
https://ncbi.nlm.nih.gov/pubmed/20700632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-010-0234-3
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