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Human centromeres produce chromosome-specific and array-specific alpha satellite transcripts that are complexed with CENP-A and CENP-C

Human centromeres are defined by alpha satellite DNA arrays that are distinct and chromosome-specific. Most human chromosomes contain multiple alpha satellite arrays that are competent for centromere assembly. Here, we show that human centromeres are defined by chromosome-specific RNAs linked to und...

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Publicat a:Dev Cell
Autors principals: McNulty, Shannon M., Sullivan, Lori L., Sullivan, Beth A.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568664/
https://ncbi.nlm.nih.gov/pubmed/28787590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.07.001
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