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Genomic size of CENP-A domain is proportional to total alpha satellite array size at human centromeres and expands in cancer cells

Human centromeres contain multi-megabase-sized arrays of alpha satellite DNA, a family of satellite DNA repeats based on a tandemly arranged 171bp monomer. The centromere-specific histone protein CENP-A is assembled on alpha satellite DNA within the primary constriction, but does not extend along it...

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Autors principals: Sullivan, Lori L., Boivin, Christopher D., Mravinac, Brankica, Song, Ihn Young, Sullivan, Beth A.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565466/
https://ncbi.nlm.nih.gov/pubmed/21484447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10577-011-9208-5
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