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Genomic size of CENP-A domain is proportional to total alpha satellite array size at human centromeres and expands in cancer cells
Human centromeres contain multi-megabase-sized arrays of alpha satellite DNA, a family of satellite DNA repeats based on a tandemly arranged 171bp monomer. The centromere-specific histone protein CENP-A is assembled on alpha satellite DNA within the primary constriction, but does not extend along it...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3565466/ https://ncbi.nlm.nih.gov/pubmed/21484447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10577-011-9208-5 |
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