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Anticancer efficacy of Apo2L/TRAIL is retained in the presence of high and biologically active concentrations of osteoprotegerin in vivo

Osteoprotegerin (OPG) is a secreted member of the tumor necrosis factor (TNF) receptor superfamily that binds to the ligand for receptor activator of nuclear factor κB (RANKL) and inhibits bone resorption. OPG can also bind and inhibit the activity of the TNF‐related apoptosis‐inducing ligand (Apo2L...

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Détails bibliographiques
Publié dans:J Bone Miner Res
Auteurs principaux: Zinonos, Irene, Labrinidis, Agatha, Lee, Michelle, Liapis, Vasilios, Hay, Shelley, Ponomarev, Vladimir, Diamond, Peter, Findlay, David M, Zannettino, Andrew CW, Evdokiou, Andreas
Format: Artigo
Langue:Inglês
Publié: Wiley Subscription Services, Inc., A Wiley Company 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568243/
https://ncbi.nlm.nih.gov/pubmed/20818644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.244
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