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Anticancer efficacy of Apo2L/TRAIL is retained in the presence of high and biologically active concentrations of osteoprotegerin in vivo
Osteoprotegerin (OPG) is a secreted member of the tumor necrosis factor (TNF) receptor superfamily that binds to the ligand for receptor activator of nuclear factor κB (RANKL) and inhibits bone resorption. OPG can also bind and inhibit the activity of the TNF‐related apoptosis‐inducing ligand (Apo2L...
Enregistré dans:
Publié dans: | J Bone Miner Res |
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Auteurs principaux: | , , , , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
Wiley Subscription Services, Inc., A Wiley Company
2011
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5568243/ https://ncbi.nlm.nih.gov/pubmed/20818644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.244 |
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