Tetanus toxin is a zinc protein and its inhibition of neurotransmitter release and protease activity depend on zinc.

Tetanus and botulinum neurotoxins are the most potent toxins known. They bind to nerve cells, penetrate the cytosol and block neurotransmitter release. Comparison of their predicted amino acid sequences reveals a highly conserved segment that contains the HexxH zinc binding motif of metalloendopepti...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Schiavo, G, Poulain, B, Rossetto, O, Benfenati, F, Tauc, L, Montecucco, C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556816/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1396558/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1992.tb05441.x
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