Tetanus toxin is a zinc protein and its inhibition of neurotransmitter release and protease activity depend on zinc.

Tetanus and botulinum neurotoxins are the most potent toxins known. They bind to nerve cells, penetrate the cytosol and block neurotransmitter release. Comparison of their predicted amino acid sequences reveals a highly conserved segment that contains the HexxH zinc binding motif of metalloendopepti...

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Dettagli Bibliografici
Pubblicato in:EMBO J
Autori principali: Schiavo, G, Poulain, B, Rossetto, O, Benfenati, F, Tauc, L, Montecucco, C
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1992
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556816/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1396558/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1992.tb05441.x
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