Tetanus toxin is a zinc protein and its inhibition of neurotransmitter release and protease activity depend on zinc.

Tetanus and botulinum neurotoxins are the most potent toxins known. They bind to nerve cells, penetrate the cytosol and block neurotransmitter release. Comparison of their predicted amino acid sequences reveals a highly conserved segment that contains the HexxH zinc binding motif of metalloendopepti...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Schiavo, G, Poulain, B, Rossetto, O, Benfenati, F, Tauc, L, Montecucco, C
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 1992
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556816/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1396558/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1992.tb05441.x
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