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Fine epitope mapping of two antibodies neutralizing the Bordetella adenylate cyclase toxin

Adenylate cyclase toxin (ACT) is an important B. pertussis virulence factor that is not included in current acellular pertussis vaccines. We previously demonstrated that immunization with the repeat-in-toxin (RTX) domain of ACT elicits neutralizing antibodies in mice and discovered the first two ant...

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Bibliografski detalji
Izdano u:Biochemistry
Glavni autori: Wang, Xianzhe, Stapleton, James A., Klesmith, Justin R., Hewlett, Erik L., Whitehead, Timothy A., Maynard, Jennifer A.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568097/
https://ncbi.nlm.nih.gov/pubmed/28177609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01163
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