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Fine epitope mapping of two antibodies neutralizing the Bordetella adenylate cyclase toxin

Adenylate cyclase toxin (ACT) is an important B. pertussis virulence factor that is not included in current acellular pertussis vaccines. We previously demonstrated that immunization with the repeat-in-toxin (RTX) domain of ACT elicits neutralizing antibodies in mice and discovered the first two ant...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Wang, Xianzhe, Stapleton, James A., Klesmith, Justin R., Hewlett, Erik L., Whitehead, Timothy A., Maynard, Jennifer A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568097/
https://ncbi.nlm.nih.gov/pubmed/28177609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01163
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