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Fine epitope mapping of two antibodies neutralizing the Bordetella adenylate cyclase toxin

Adenylate cyclase toxin (ACT) is an important B. pertussis virulence factor that is not included in current acellular pertussis vaccines. We previously demonstrated that immunization with the repeat-in-toxin (RTX) domain of ACT elicits neutralizing antibodies in mice and discovered the first two ant...

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Bibliografiske detaljer
Udgivet i:Biochemistry
Main Authors: Wang, Xianzhe, Stapleton, James A., Klesmith, Justin R., Hewlett, Erik L., Whitehead, Timothy A., Maynard, Jennifer A.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568097/
https://ncbi.nlm.nih.gov/pubmed/28177609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01163
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