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Targeting the homologous recombination pathway by small molecule modulators

During the last decade, the use of small molecule (MW< 500 Dalton) compounds that modulate (inhibit or activate) important proteins of different biological pathways became widespread. Recently, the homologous recombination (HR) pathway emerged as a target for such modulators. Development of small...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: Huang, Fei, Mazin, Alexander V
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568029/
https://ncbi.nlm.nih.gov/pubmed/24856061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.04.088
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