Analogs of the ATP-Sensitive Potassium (K(ATP)) Channel Opener Cromakalim with in Vivo Ocular Hypotensive Activity

K(ATP) channel openers have emerged as potential therapeutics for the treatment of glaucoma, lowering intraocular pressure in animal models and cultured human anterior segments. We have prepared water soluble phosphate and dipeptide derivatives of the K(ATP) channel opener cromakalim and evaluated t...

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Bibliografiset tiedot
Julkaisussa:J Med Chem
Päätekijät: Chowdhury, Uttio Roy, Viker, Kimberly B., Stoltz, Kristen L., Holman, Bradley H., Fautsch, Michael P., Dosa, Peter I.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567990/
https://ncbi.nlm.nih.gov/pubmed/27367033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.6b00406
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