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Analogs of the ATP-Sensitive Potassium (K(ATP)) Channel Opener Cromakalim with in Vivo Ocular Hypotensive Activity
K(ATP) channel openers have emerged as potential therapeutics for the treatment of glaucoma, lowering intraocular pressure in animal models and cultured human anterior segments. We have prepared water soluble phosphate and dipeptide derivatives of the K(ATP) channel opener cromakalim and evaluated t...
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| 出版年: | J Med Chem |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5567990/ https://ncbi.nlm.nih.gov/pubmed/27367033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.6b00406 |
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