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MnTE-2-PyP Treatment, or NOX4 Inhibition, Protects against Radiation-Induced Damage in Mouse Primary Prostate Fibroblasts by Inhibiting the TGF-Beta 1 Signaling Pathway

Prostate cancer patients who undergo radiotherapy frequently suffer from side effects caused by radiation-induced damage to normal tissues adjacent to the tumor. Exposure of these normal cells during radiation treatment can result in tissue fibrosis and cellular senescence, which ultimately leads to...

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Detalhes bibliográficos
Publicado no:Radiat Res
Main Authors: Chatterjee, Arpita, Kosmacek, Elizabeth A., Oberley-Deegan, Rebecca E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567913/
https://ncbi.nlm.nih.gov/pubmed/28225655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR14623.1
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