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The Metalloporphyrin Antioxidant, MnTE-2-PyP, Inhibits Th2 Cell Immune Responses in an Asthma Model

MnTE-2-PyP, a superoxide dismutase mimetic, inhibited OVA-induced airway inflammation in mice suggesting an effect on Th2 responsiveness. Thus, we hypothesized that MnTE-2-PyP may alter dendritic cell-Th2 interactions. Bone marrow derived dendritic cells (DC) and OVA(323–339)-specific Th2 cells were...

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Détails bibliographiques
Auteurs principaux: Jungsuwadee, Paiboon, Weaver, Michael R., Gally, Fabienne, Oberley-Deegan, Rebecca E.
Format: Artigo
Langue:Inglês
Publié: Molecular Diversity Preservation International (MDPI) 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431828/
https://ncbi.nlm.nih.gov/pubmed/22949830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13089785
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