The NF-kappa B p50 precursor, p105, contains an internal I kappa B-like inhibitor that preferentially inhibits p50.

The p50 subunit of NF-kappa B is apparently synthesized as a precursor molecule of 105 kDa (p105); subsequent processing releases the amino-terminal p50 polypeptide with rel homology, DNA binding activity and transcriptional activation potential. The carboxy-terminal region of p105 contains seven co...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Liou, H C, Nolan, G P, Ghosh, S, Fujita, T, Baltimore, D
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 1992
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556782/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1639070/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1992.tb05370.x
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