The ankyrin repeat domains of the NF-kappa B precursor p105 and the protooncogene bcl-3 act as specific inhibitors of NF-kappa B DNA binding.

The inducible pleiotropic transcription factor NF-kappa B is composed of two subunits, p50 and p65. The p50 subunit is encoded on the N-terminal half of a 105-kDa open reading frame and contains a rel-like domain. To date, no function has been described for the C-terminal portion. We show here that...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Hatada, E N, Nieters, A, Wulczyn, F G, Naumann, M, Meyer, R, Nucifora, G, McKeithan, T W, Scheidereit, C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48684/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1532257/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.6.2489
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