The oncoprotein Bcl-3 can facilitate NF-kappa B-mediated transactivation by removing inhibiting p50 homodimers from select kappa B sites.

Previously we have proposed a role for Bcl-3 in facilitating transactivation through kappa B sites by counteracting the inhibitory effects of bound, non-transactivating homodimers of the p50 subunit of NF-kappa B. Such homodimers are abundant for example in nuclei of unstimulated primary T cells. He...

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Dades bibliogràfiques
Publicat a:EMBO J
Autors principals: Franzoso, G, Bours, V, Azarenko, V, Park, S, Tomita-Yamaguchi, M, Kanno, T, Brown, K, Siebenlist, U
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1993
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413672/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8404857/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb06067.x
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