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The oncoprotein Bcl-3 can facilitate NF-kappa B-mediated transactivation by removing inhibiting p50 homodimers from select kappa B sites.

Previously we have proposed a role for Bcl-3 in facilitating transactivation through kappa B sites by counteracting the inhibitory effects of bound, non-transactivating homodimers of the p50 subunit of NF-kappa B. Such homodimers are abundant for example in nuclei of unstimulated primary T cells. He...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Franzoso, G, Bours, V, Azarenko, V, Park, S, Tomita-Yamaguchi, M, Kanno, T, Brown, K, Siebenlist, U
פורמט: Artigo
שפה:Inglês
יצא לאור: 1993
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC413672/
https://ncbi.nlm.nih.gov/pubmed/8404857
תגים: הוספת תג
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