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Identification of IL-1β-producing monocytes that are susceptible to pyronecrotic cell death in patients with NOMID
OBJECTIVE: Spontaneous inflammatory responses initiated by NLRP3 mutations promote inflammasome-mediated IL-1β processing and release, and can induce rapid necrotic cell death. The cells that produce IL-1β in neonatal onset multisystem inflammatory disease (NOMID) have not been clearly identified, n...
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| Udgivet i: | Arthritis Rheumatol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5567735/ https://ncbi.nlm.nih.gov/pubmed/26245468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39307 |
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