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Human Autoinflammatory Diseases Mediated by NLRP3-, Pyrin-, NLRP1-, and NLRC4-Inflammasome Dysregulation Updates on Diagnosis, Treatment, and the Respective Roles of IL-1 and IL-18

Recent research has led to novel findings in inflammasome biology and genetics that altered the diagnosis and management of patients with autoinflammatory syndromes caused by NLRP3-, Pyrin-, NLRP1-, and NLRC4-inflammasomes and spurred the development of novel treatments. The use of next-generation s...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Alehashemi, Sara, Goldbach-Mansky, Raphaela
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7477077/
https://ncbi.nlm.nih.gov/pubmed/32983099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01840
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