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IL-1 Blockade in Autoinflammatory Syndromes

Monogenic autoinflammatory syndromes present with excessive systemic inflammation including fever, rashes, arthritis, and organ-specific inflammation and are caused by defects in single genes encoding proteins that regulate innate inflammatory pathways. Pathogenic variants in two interleukin-1 (IL-1...

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Bibliografiske detaljer
Main Authors: Jesus, Adriana A., Goldbach-Mansky, Raphaela
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178953/
https://ncbi.nlm.nih.gov/pubmed/24422572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-med-061512-150641
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