Tumour ischaemia by interferon-γ resembles physiological blood vessel regression

The relative contribution of the effector molecules produced by T cells to tumour rejection is unclear, but interferon-γ (IFNγ) is critical in most of the analysed models(1). Although IFNγ can impede tumour growth by acting directly on cancer cells(2,3), it must also act on the tumour stroma for eff...

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Publicat a:Nature
Autors principals: Kammertoens, Thomas, Friese, Christian, Arina, Ainhoa, Idel, Christian, Briesemeister, Dana, Rothe, Michael, Ivanov, Andranik, Szymborska, Anna, Patone, Giannino, Kunz, Severine, Sommermeyer, Daniel, Engels, Boris, Leisegang, Matthias, Textor, Ana, Fehling, Hans Joerg, Fruttiger, Marcus, Lohoff, Michael, Herrmann, Andreas, yu, Hua, Weichselbaum, Ralph, Uckert, Wolfgang, Hübner, Norbert, Gerhardt, Holger, Beule, Dieter, Schreiber, Hans, Blankenstein, Thomas
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567674/
https://ncbi.nlm.nih.gov/pubmed/28445461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22311
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